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An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry
Author: Graham L. Patrick
ISBN 13: 9780199234479
ISBN 10: 199234477
Edition: 4th
Publisher: Oxford University Press
Publication Date: 2009-03-25
Format: Paperback
Pages: 752
List Price: $67.99

Of particular interest to those considering entering the pharmaceutical industry, this textbook introduces undergraduates and postgraduates to the fundamentals of medicinal chemistry. A four-part structure guides the reader from a discussion of the biological environment in which drugs act, through the drug discovery and development process, and on to case studies of drug types. The third edition features four new chapters covering pharmacokinetics, antiviral agents, anticancer agents, and drug discovery. Annotation ©2005 Book News, Inc., Portland, OR

Matthias C. Lu

This is an excellent new text that illustrates how chemical and biochemical concepts could be used for a better understanding of drug action at the cellular level. In this short treatise, the author presents an excellent overview of how drugs can be developed based on a good foundation of these principles. The purpose is to convey to the reader the fascination of working in a field such as field of medicinal chemistry, which overlaps the disciplines of chemistry, biochemistry, cell biology, and pharmacology. This book is specifically targeted for undergraduates who have a basic chemistry background and are interested in a future career in the pharmaceutical industry. With this intention in mind, this book is timely and has largely fulfilled its overall objective. However, in my opinion this book can also serve as an introductory text to medicinal chemistry courses in the pharmacy curriculum if the introductory chapters are expanded and certain errors are corrected. The author should be commended for an excellent presentation of chemical aspects of antibacterial agents, opiate analgesics, and histamine antagonists as antiulcer drugs. However, the inclusion of cartoons in this text is not necessary. This is a excellent text for anyone who has a basic knowledge of organic chemistry and is interested in learning medicinal chemistry. The practicing pharmacists who wish to refresh their medicinal chemistry background or would like to learn how to apply the principles of medicinal chemistry in their practice should find this text useful. In conclusion, this is a very good book and with some modifications it can be used as an introductory text to a medicinal chemistry course in the pharmacycurriculum.