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Medicinal Natural Products: A Biosynthetic Approach

Medicinal Natural Products: A Biosynthetic Approach
Author: Paul M. Dewick
ISBN 13: 9780470741672
ISBN 10: 470741678
Edition: 3
Publisher: Wiley
Publication Date: 2009-03-09
Format: Paperback
Pages: 539
List Price: $76.00

Medicinal Natural Products, Second Edition provides a comprehensive and balanced introduction to natural products from a biosynthetic perspective. The book builds upon fundamental chemical principles and guides the reader through a wealth of diverse natural metabolites with particular emphasis on those used in medicine: sources, production methods, use as drugs, semi-synthetic derivatives and synthetic analogues, and modes of action are all extensively covered. Invaluable for students of pharmacy, medicinal chemistry, pharmacognosy, phytochemistry and chemistry.

The Second Edition retains the user-friendly style and highly acclaimed features of the First Edition, and has been extended and fully updated:

* A comprehensive treatment of plant, microbial and animal products natural products in one volume including the latest developments in the field.

* Expanded coverage of many topics.

* New material including genetic manipulation of biosynthetic pathways and the mevalonate-independent pathway to terpenoids.

* Extensive use of chemical schemes with annotated mechanistic explanations.

* Cross-referencing to emphasize links and similarities.

Reviews of the First Edition:

"...one of the best books on natural products that has been written. It should find a place on the bookshelves of everyone with an interest in natural products, since it not only offers a quick overview of the many different facets of natural products chemistry, but also, thanks to its comprehensive index, serves as an excellent reference source." Angewandte Chemie.

"Paul Dewick's enthusiasm for his subject is much in evidence, and this book will be both welcomed and enjoyed by all those who want to know the basic facts about medicinal natural products." Phytochemistry. "It is refreshing to read a current natural products textbook that embraces a biosynthetic approach to instruction, which allows for the application of basic chemical principles. This text is invaluable for both undergraduate and graduate students with interests in natural products chemistry" Journal of Natural Products. "...this book is excellent, with high quality of both text and illustrations throughout...I would recommend purchase for all those who are interested in the biosynthetic pathways of medicinal natural products." Trends in Plant Science.


This comprehensive guide to pharmacognosy, the scientific study of natural health remedies from herbs, animal products, and inorganic materials, is directed primarily toward undergraduate students— whether or not such material is integrated with traditional pharmacy courses. Dewick (pharmaceutical sciences, U. of Nottingham, UK) provides a foundation in natural product chemistry/phytochemistry and nomenclature before proceeding to coverage of the primary and secondary metabolism of the reactions of these diverse substances; and the pathways involved in the biosynthesis of several classes of popular natural medicines represented by echinacea, kava, feverfew, taxol, alkaloids, garlic, and various vitamins. The chapters include molecular structure diagrams, boxed material, and further reading. Annotation c. Book News, Inc., Portland, OR (booknews.com)